Which of the following documents provides guidance for safeguarding classified information?

The document that provides guidance for safeguarding classified information is indeed the DoDM 5200.01. This directive is part of the Department of Defense’s suite of instructions focused on the protection of classified and sensitive unclassified information across the department. It outlines the policies, procedures, and responsibilities for employees related to the proper handling, storage, and transmission of classified information, ensuring compliance with federal laws and regulations regarding national security.

With foundational policies such as this, personnel can understand their duties and the relevant security measures needed to mitigate the risks associated with unauthorized disclosures. In contrast, other options may not specifically address safeguarding classified information or may pertain to different aspects of security or governance. For instance, Executive Orders or Presidential Directives may outline broader goals or policies but do not go into the detailed guidance necessary for daily operations concerning classified information.